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Pathogens

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What are pathogen resources?

  • Pathogens such as bacteria, fungi, viruses, and protozoa that cause infectious diseases in humans, which have been validated for quality and value, along with related information that has been converted into resources
  • Information related to pathogen origin, naturally occurring cellular resources, antigens, antibodies, and other derivatives

Applications

Research for vaccine and therapeutic development
Research for diagnostic development
Quality control
Research for product development
Education

Why is pathogen research and industry development important?

  • Increase in the economic value of pathogens, following the enforcement of the Convention on Biological Diversity (CBD) and the Nagoya Protocol
  • Necessary to strategically secure useful overseas pathogen resources and to ensure domestic pathogen resources
  • Required to develop diagnostics, preventive vaccines, and therapeutics due to the introduction of emerging infectious diseases from abroad and domestic outbreaks

Active R&D investment in pathogen resources for vaccine, diagnostic, and therapeutic development, with selection and support for development as a national strategic life science resource

Pathogen resource-based research cases

Early Evolutionary Lineage and Mutation Analysis of COVID-19 Virus Outbreak
  • Conducted by the National Institute of Infectious Diseases, National Institute of Health, identifying the emergence timing of the common ancestor of domestic isolates, genetic mutations, and mutation stages
  • Published in the international journal ‘Heliyou’, October 2021
Development of COVID-19 Neutralizing Antibody Therapeutic (Regdanvimab)
  • Conducted by the National Institute of Infectious Diseases, National Institute of Health, jointly filing a patent with the developer for a binding molecule with neutralizing activity against SARS-CoV-2
  • The third COVID-19 monoclonal antibody therapeutic developed worldwide, currently used to treat patients domestically and internationally

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You can achieve more accurate search results by using the following operators in your search query.

Guide table of search operators and examples
Operator Function
Space Search for data that contains both search terms.
lung cancer

→ Search for data that contains both "lung" and "cancer".
| Search for data that contains either of the two search terms (at least one).
lung | cancer

→ Search for data that contains either "lung" or "cancer".
! Exclude a specific term.
Exclude data that contains the search term following NOT.
lung !cancer

→ Search for data that contains "lung" but excludes "cancer".
[ ] Search for data that exactly matches the phrase within square brackets.
IUPAC name search, long phrase search
[lung cancer]

→ Search for data that exactly matches the phrase "lung cancer".
( ) Grouping/precedence operator for complex queries.
(bio (lung | cancer) )

→ Search for data that contains either "lung" or "cancer" and also contains "bio".
* Partial match using a wildcard.
Search for data that matches the pattern where * represents zero or more characters.
canc*

→ Search for data that contains terms starting with "canc", such as "cancer" or "cancers".

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