Cluster
Stem Cells
Cluster Open
What are stem cells?
- A stem cell is a cell that has the ability to produce various types of other cells.
- They are classified into (1) adult stem cells, (2) embryonic stem cells, and (3) induced pluripotent stem cells (iPSCs).
Applications
Research on cell therapy products and the development of treatment models for intractable diseases
Toxicity testing and new drug development research
Research on foundational technologies for ensuring stem cell quality
Why is stem cell research important?
- Stem cells possess unlimited self-renewal capability and pluripotency, allowing them to differentiate into various cell types. These characteristics make them applicable across a wide range of modern medical fields, including disease modeling and new drug development.
- Because stem cells can be derived from cells or tissues that share a patient’s genetic background, they enable rapid and accurate prediction of drug efficacy. With the rise of precision medicine, their use in new drug development research has increased significantly.
- Stem cell research also contributes to a deeper understanding of human development and disease mechanisms, and it enables applications in artificial organ development. Furthermore, integration with biomedical engineering and bio-organ technologies is expanding its range of applications.
Centered around the Korea National Stem Cell Bank (KSCB), a wide variety of high-quality stem cells are being collected, stored, and distributed. Efforts are also underway to establish standardization systems for stem cells, promoting research activation and providing strong support for researchers.
About the core stem cell cluster agency
Roles and activities of the KSCB
- Since 2014, the KSCB has been culturing, expanding, and managing the quality of human pluripotent stem cells donated or developed by researchers, and distributing them for research use.
- Operates in accordance with standardized operating procedures and is certified under the ISO 9001 quality management system
Key achievements
- Distributes approximately 70–80 stem cell resources annually
- 58 research papers and 23 patent applications/registrations utilizing banked stem cells (as of Dec. 2023)
Research papers
- Development of a Novel Drug Screening Platform for Drug-Resistant Mycobacterium Tuberculosis Using Stem Cell-Derived Macrophage Differentiation Technology
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