Bio-resource Clusters
Microorganisms
Cluster OpenKorea Research Institute of Bioscience and Biotechnology Biological Resource Center (KCTC)
The KCTC discovers, acquires, and preserves biological resources, providing the life science infrastructure necessary for the full lifecycle of bio-research, from basic studies to practical applications.
The KCTC began its role as a microbial resource infrastructure institution in 1985 as a special project division of KIST’s Genetic Engineering Center. As the largest holder of standard and patented microbes in Korea, the KCTC supports the acquisition and utilization of biological resources for R&D in the bio-industry, with the vision of “Bio Korea! Global KCTC, a global microbial bank supporting a strong bio-nation.”
As Korea’s largest accredited microbial resource institution (including standard, reference, and patented strains), the KCTC is responsible for acquiring, distributing, and providing services for microbial resources, managing and distributing R&D outcomes (biological resources), supporting the bioeconomy through the development of a life resource industry ecosystem, building international life resource cooperation networks, and serving as the central microbial bank under the multi-ministerial National Life Research Resource Advancement Project launched in 2021.
- KCTC holdings of biological resources (as of December 31, 2023)
- KCTC (Standard) microbial resources and research outcome resources are managed under a 1:1 exchange coupon system for depositors.
Rural Development Administration Agricultural Microbial Bank (KACC)
The Korean Agricultural Culture Collection (KACC) collects, classifies, evaluates, and digitizes microorganisms in the agriculture and food sectors to preserve them and provide access to users.
- The KACC was established in 1995 at the National Institute of Agricultural Sciences under the Rural Development Administration, with the following missions:
- The KACC is also legally mandated to perform the following roles as a government agency
- Bacteria
- 6,757 species
-
13,738
strains
- Fungi (yeasts, molds, mushrooms)
- 3,540 species
-
15,056
strains
| Service Type | Detailed Service Type | Service Description | Application Procedure | Fee (KRW) |
|---|---|---|---|---|
| Microorganism Deposit | General Deposit | Deposited strains under general deposit are made publicly available and distributed for research, education, or industrial use. Upon depositor request, confidentiality can be maintained for up to 2 years. | Consultation with KACC staff ▶ Submit deposit application & microbial samples ▶ Strain preservation ▶ Issuance of registration number notice | Free of charge |
| Patent Deposit | Microorganisms used in inventions are deposited in accredited patent microbial repositories for domestic or international patent applications. | Submit deposit application, microbial samples & deposit fee ▶ Preservation and viability confirmation ▶ Identity verification ▶ Issuance of certificate of deposit | KRW 800,000 per strain | |
| Microorganism Distribution | General Distribution | Individuals affiliated with institutions authorized to handle microorganisms can receive up to 10 strains per request and a maximum of 20 strains per year for research and educational purposes. | Register as an online distribution member ▶ Apply for online distribution ▶ Receive approval ▶ Shipment of microbial strains | Free of charge |
| Special Distribution | Requests exceeding 20 strains per year for research or educational purposes require submission of a project plan and approval before distribution. | Consultation with KACC staff ▶ Submit project plan ▶ Apply for online distribution ▶ Shipment of microbial strains | Free of charge | |
| Industrial Distribution | For industrial use, a separate distribution agreement must be signed among the original depositor, KACC, and the applicant when requesting strains. | Consultation with KACC staff ▶ Prepare industrial use distribution agreement (applicant, original depositor, and KACC representative) ▶ Distribution | Free / Paid (depending on service type) | |
| Microorganism Preservation & Education Services | Safe Preservation Service | Microorganisms with high utilization potential by companies, universities, or research institutes, but not registered as national resources and at risk of loss, are redundantly preserved in KACC’s liquid nitrogen tanks and ultra-low temperature freezers. | Consultation with KACC staff ▶ Prepare safety preservation agreement ▶ Depositor directly stores strains in KACC preservation facilities | Free of charge |
| Workshop | International workshops on food and indoor fungi are conducted, providing training on isolation, identification, and classification of food-contaminating and fermentative fungi. | Held annually in September ▶ Apply online via the KACC website | Paid |
Environmental Microbial Resource & Gene Base Bank
As the only environmental microbial resource center in Korea, we aim to serve as a global professional microbial preservation bank that provides essential resources for basic research and industrial applications.
Since the 1970s, the Environmental Microbial Resources and Gene Bank has conducted classification, phylogenetic studies, and environmental pollution control research related to microbial resources, developing and securing unique domestic environmental microbial and genetic resources.
Designated in 2005 by the Ministry of Science and ICT as a specialized microbial resources bank, we have established and operated an efficient management system to effectively preserve and secure domestic environmental microbial resources, providing foundational data for the classification and ecological studies of indigenous microorganisms.
The need for applied technology development using useful biological resources and the operation of specialized biological resource centers has become increasingly significant worldwide, particularly since the adoption of the Nagoya Protocol under the Convention on Biological Diversity (CBD) in 2010.
Ecosystem destruction and biodiversity loss continue to worsen due to rapid industrialization and urbanization, leading to ongoing environmental degradation—necessitating appropriate countermeasures.
There is a growing need for research and development of economical and efficient biological treatment methods to restore damaged ecosystems, along with heightened awareness of the national role of professional microbial preservation institutions that systematically collect and distribute microbial resources to support such efforts.
The Environmental Microbial Resources and Gene Bank isolates, identifies, and characterizes valuable research strains for the removal of pollutants from water, soil, and marine environments, preserving and utilizing these microbial resources and related genes for bioenvironmental research and industrial applications.
The developed microbial resources are provided to academia, research institutes, and industries, contributing to the advancement of related scientific fields and industrial sectors.
In addition, we are building infrastructure for establishing a world-class resource center and providing foundational data in life science and environmental engineering to support biological treatment research for pollution removal and ecosystem restoration.
| Service Type | Detailed Service Type | Service Description | Application Procedure | Fee (KRW) |
|---|---|---|---|---|
| Microbial Deposit | Preservation and Utilization Support for Developed Resources |
|
|
Free of charge |
| Distribution of Microbial Resources | Distribution of Environmental Microbial Research Materials | Distribution of environmental microbial research materials |
|
|
| Support for Utilization of Microbial Resources | Workshops/Seminars (Regular/Occasional) | Establishes networks and facilitates technology transfer for the utilization of related resources | Application via phone or online | Free of charge |
| Education Programs (Occasional) | Provides training programs on core technologies for microbial resource preservation | Application via phone or online | Free of charge |
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