헤더로 바로가기 본문으로 바로가기

검색 폼

Synthetic Compounds

Cluster Open
Korea Chemical Bank

Korea Research Institute of Chemical Technology Korea Chemical Bank

The KCB utilizes advanced facilities and automated equipment, as well as computer servers and programs, to collect, store, distribute, manage quality, and analyze new drug compound materials and data, ensuring fast and accurate distribution.

Established in 2000, the KCB is a core infrastructure for new drug development and biotechnology research, jointly utilizing domestic compound resources and related information. In 2008, it was designated as the compound research outcome management and distribution agency for national research and development projects by the Ministry of Science and ICT. KCB performs the role of the central bank for synthetic compound clusters and was designated as a bio-resource deposit and preservation agency in 2022.

Located within the Korea Research Institute of Chemical Technology (KRICT) in Yuseong-gu, Daejeon, the KCB operates large-scale freezers for compound storage, AutoStorage equipment for storing and selecting DMSO solutions for distribution, liquid handler for automatic dispensing, and advanced facilities for quality control and analysis. The institute also employs computer servers and programs for fast and accurate compound and data distribution.
The KCB holds over 750,000 types of new drug compound materials (as of 2024) and has provided more than 11.2 million compounds for approximately 1,300 projects across academia, industry, and research over the past 20 years, securing more than 8.8 million compound utilization efficacy data entries.

In 2020, the KCB integrated its physical and information management databases with international public databases into a unified data platform. This platform provides compound search services without login, and after logging in through the NTIS, it offers compound selection and management based on user needs, automated virtual screening, and support for deposit and distribution.

  • Novel Drug Discovery Compounds
  • approximately
  • 78

    types
  • Distribution
  • 1,574

    projects
  • Compound Distribution
  • approximately
  • 1,120

    items
  • Compound-Based Pharmacological Data
  • approximately
  • 1,060

    records
한국화학연구원 한국화합물은행 logo
[합성화합물 클러스터] 한국화학연구원 한국화합물은행의 서비스에 관한 표입니다. - 서비스 유형/세부서비스 유형/서비스 내용/신청절차/단가(원) (VAT 10% 별도) 로 구성되어있습니다.
Service Type Detailed Service Type Service Description Application Procedure Fee (KRW) (VAT 10% excluded)
Compound Deposit Compound Deposit Application and Validation
  • Receives drug discovery compounds, verifies their drug-like properties and quality, and registers research results in the NTIS
  • Range and criteria for deposit compounds
    • Range: Organic synthesis compounds, single-component natural products
    • Criteria: Compound amount: Solid > 10mg, Oil > 20mg (recommended)
    • Purity: ≥ 80% (verified by UPLC-MS at KCB), 1H-NMR data submission required
Access the integrated data platform ▶ Log in via NTIS ▶ Submit deposit application ▶ Register compound structure and required information ▶ Suitability review ▶ Ship compound (KCB quality verification) ▶ Register in KCB database and NTIS ▶ Issue deposit certificate -
Resource Distribution Compound Distribution
  • Primary screening (single concentration) distribution
    • Selected compound distribution: User-selected or KCB-assisted selection
    • Pre-made compound distribution: Representative, clinical, natural products, fragment, kinase, PPI, GPCR, etc.
  • Secondary screening (validation) distribution
    • Active substance confirmation (multiple concentrations) distribution
    • Active substance derivative distribution
Access the integrated data platform ▶ Log in via NTIS ▶ Submit utilization application and efficacy test report ▶ Review for duplication and suitability ▶ Utilization agreement ▶ Compound distribution ▶ Receive efficacy test results ▶ Provide compound structure information, purity analysis results, and related information
  • Compounds are provided free of charge with actual cost
    • 96-well (80 compounds/plate): KRW 30,400
    • 384-well (320 compounds/plate): KRW 117,100
  • 50% of the actual cost charged to small/venture companies, universities, and public research institutes
Data Distribution
  • Compound structure data
  • Publicly available compound activity data
*Data provided on USB
Submit utilization application (main email)* ▶ Data utilization agreement ▶ Request for data distribution ▶ Receive data analysis results
*To be provided on the integrated data platform site in 2024
Free
Technical Support Expert Support for Compound Selection
  • Structure-based virtual screening
  • Ligand-based virtual screening
  • Pathway information-based selection
  • Derivative selection
Email application and compound selection support after expert consultation Free
Provision of Active and Hit Analysis Reports Quality verification and related information services for Active and Hit compounds Provides analysis reports and related information upon the identification of active and hit compounds Free
User-based Compound Search and Selection Compound Search Integrated search service utilizing structure information, drug names, structural formulas, and characteristic data (KCB, ChEMBL, DrugBank, PDB) Access the integrated data platform ▶ Search (available without login) ▶ Keyword search, structure search, property search, disease search, target search, SDF file search ▶ Confirm compound structure from search results Free
My Library Uses search results to select compounds, stores them in My Library, and applies for compound distribution Access the integrated data platform ▶ Log in via NTIS ▶ Search ▶ Select compound from search results page ▶ Save to My Library ▶ Use for compound distribution request
Virtual Screening Projects Selects compounds expected to bind to target proteins by extracting pharmacophore features based on protein-ligand binding structures Access the integrated data platform ▶ Log in via NTIS ▶ Projects ▶ Virtual screening ▶ Register virtual screening project ▶ Enter PDB code and search ▶ Select key ligands ▶ Generate pharmacophore feature ▶ Select features (recommended combinations or individual selections available) ▶ Select virtual screening library ▶ Perform virtual screening ▶ Select compounds from search results ▶ Save to My Library ▶ Use for compound distribution request

Starting access logging.

Help FAQ
TOP